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Literature summary extracted from

  • Gc, K.; To, D.; Jayalath, K.; Abeysirigunawardena, S.
    Discovery of a novel small molecular peptide that disrupts helix 34 of bacterial ribosomal RNA (2019), RSC Adv., 9, 40268-40276 .
No PubMed abstract available

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.1.1.172 expression in Escherichia coli Escherichia coli

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.1.1.172 KNHDWGV 7-mer peptide that binds to the second strand of 16S h34 RNA. Binding of the peptide alters RNA structure and inhibits the binding of the ribosomal RNA small subunit methyltransferase C. The addition of the peptide also increases the lag phase of bacterial growth Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.172 Escherichia coli
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.1.1.172 recombinant protein Escherichia coli

Synonyms

EC Number Synonyms Comment Organism
2.1.1.172 RsmC
-
 Escherichia coli